5 Best Topical Pain Relievers for Neuropathy

I've found relief from neuropathic pain using these top 5 topical pain relievers. From lidocaine cream to CBD topicals, these treatments have provided me with much-needed comfort. If you're suffering from neuropathy, you'll want to explore these options for managing your discomfort.

Key Takeaways

  • Lidocaine cream and capsaicin patch are effective options for relieving neuropathic pain.
  • Menthol gel and NSAID cream provide temporary relief and help reduce the intensity of neuropathic pain.
  • CBD topical offers localized application and shows promise in alleviating neuropathic pain.
  • Proper application techniques and consultation with a healthcare professional are crucial for maximum effectiveness and minimizing potential side effects.

Lidocaine Cream

I find lidocaine cream to be effective in relieving neuropathic pain. When applying lidocaine cream, it's crucial to follow the recommended application techniques to ensure its effectiveness. Applying a thin layer of the cream to the affected area and gently massaging it in can help maximize its pain-relieving benefits. However, it's important to be mindful of potential side effects, especially with long-term use. While lidocaine cream is generally well-tolerated, some individuals may experience redness, irritation, or a numbing sensation at the application site. Long-term use of lidocaine cream may also lead to skin sensitization or allergic reactions in some cases. Therefore, it's essential to use lidocaine cream as directed and consult a healthcare professional if any concerning side effects arise during its use.

Capsaicin Patch

After using lidocaine cream for neuropathic pain relief, I found the capsaicin patch to be another effective option. The capsaicin patch benefits include targeted pain relief, reduced inflammation, and improved blood flow in the affected area. I was initially hesitant about trying it, but I found that the patch provided long-lasting relief without the side effects often associated with oral medications. The application techniques were simple, and I appreciated the convenience of a once-daily application. It's important to note that the initial application may cause a warming or burning sensation, but this gradually decreases with regular use. The capsaicin patch has significantly improved my quality of life, allowing me to manage neuropathic pain more effectively.

Menthol Gel

Having experienced relief from neuropathic pain using the capsaicin patch, I turned to menthol gel as another topical option for managing my discomfort. Menthol gel provides a cooling sensation that helps soothe the nerves and alleviate the burning or tingling sensations associated with neuropathy. When applied to the affected area, the menthol gel creates a cooling effect that distracts from the pain and provides temporary relief. The cooling sensation can help reduce the intensity of the neuropathic pain, offering a sense of comfort and ease. Additionally, menthol gel is known for its pain-relieving properties, making it a valuable option for individuals seeking topical solutions for neuropathy. I found that applying menthol gel regularly provided me with some relief, particularly during flare-ups of neuropathic pain.


The menthol gel's cooling effect provided me with temporary relief from neuropathic pain, and now I turn to an NSAID cream for further pain management. When considering an NSAID cream for neuropathic pain, it's important to understand the application frequency and potential side effects:

  1. Application Frequency: Using the NSAID cream as directed is crucial for maximum effectiveness. Applying it consistently at the recommended intervals can help maintain a steady level of pain relief.
  2. Potential Side Effects: Like any medication, NSAID creams may have potential side effects such as skin irritation, rash, or allergic reactions. It's essential to monitor for any adverse reactions and consult a healthcare professional if any concerns arise.

Choosing the right NSAID cream and using it responsibly can provide effective relief while minimizing the risk of side effects.

CBD Topical

Turning to CBD topical for neuropathic pain has provided me with an alternative approach to managing my discomfort. CBD topicals, such as creams and salves, offer a localized application technique, allowing for targeted relief. The absorption rate of CBD topicals varies based on factors such as the product's formulation and the individual's skin type. In terms of efficacy, CBD topicals have shown promise in alleviating neuropathic pain, potentially due to their interaction with the endocannabinoid system. However, it's essential to note that individual responses may vary. As for potential side effects, while rare, some individuals may experience skin irritation or allergic reactions. When considering CBD topicals, it's crucial to consult with a healthcare professional to determine the most suitable option for managing neuropathic pain.

Aspect Details
Application technique Localized, targeted relief
Absorption rate Varies based on formulation and skin type
Efficacy Promising for alleviating neuropathic pain
Potential side effects Rare, may include skin irritation or allergic reactions

Frequently Asked Questions

Can I Use Lidocaine Cream in Combination With Other Topical Pain Relievers for Neuropathy?

Yes, I can use lidocaine cream with other topical pain relievers for neuropathy. It's important to discuss with a healthcare provider before combining them to ensure safety and effectiveness. There are alternative treatments worth exploring as well.

Are Capsaicin Patches Safe to Use on Sensitive Skin Areas Affected by Neuropathy?

Yes, capsaicin patches can be safe to use on sensitive skin areas affected by neuropathy. However, it's important to be cautious as capsaicin application may cause skin irritation, especially on sensitive skin.

Is Menthol Gel Safe to Use on Open Wounds or Broken Skin Caused by Neuropathy?

Yes, menthol gel can be safe to use on open wounds caused by neuropathy, but it's important to ensure the skin safety. It's essential to consult a healthcare professional before applying any topical treatment.

Can NSAID Cream Interact With Other Medications Commonly Used to Treat Neuropathy?

NSAID cream can interact with other medications used for neuropathy. It's important to consider potential drug interactions when using NSAID cream in combination therapy. This is especially relevant when combining with Lidocaine cream.

What Is the Recommended Dosage and Application Frequency for CBD Topical Products for Neuropathy Pain Relief?

I find that CBD topical products for neuropathy pain relief are often recommended for their effectiveness. It's important to follow the recommended dosage frequency and application techniques provided by the manufacturer for best results.


After trying out various topical pain relievers for my neuropathy, I can confidently say that lidocaine cream, capsaicin patch, menthol gel, NSAID cream, and CBD topical have been the most effective for me. Each of these options provides targeted relief and can be easily applied to the affected area. Whether it's numbing the pain with lidocaine or soothing with menthol, I've found relief with these topicals and recommend them to others dealing with neuropathic pain.

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